Mare Reproductive Loss Syndrome Essay Example | Topics and Well Written Essays - 500 words

Mare Reproductive Loss Syndrome - Essay Example t the weather at that time in March was unusually cold followed by above normal temperatures in April, which stimulated rapid plant growth and concurrent increase in the number of eastern tent caterpillars. Wild Cherry trees were the principal source of food for these caterpillars. Lack of abortion in areas where these caterpillars did not exist and later experimental intragastric inoculation of pregnant mares with caterpillar extracts confirmed the reason for these abortions (merckvetmanual.com). The MRLS syndrome in addition to early/late fetal loss is characterized by uveitis, pericarditis and encephalitis and occurs due to tissue penetration by barbed setal fragments from Eastern tent caterpillars, Malacosoma americanum (Tobin et al, 2004). After ingestion the barbed setal fragments migrate through moving tissues followed by rapid spread of bacteria, bacterial emboli and septic fragments of setae, collectively known as septic materials (Tobin et al, 2004). A number of bacteria are carried by the setal fragments in moving tissues, blood, uterus and fetal membranes of pregnant mares. Pharmacokinetic studies and studies on the structure of the setae revealed barbs on them which facilitated the rapid spread of bacteria as hitchhikers. Clinically affected tissues show a poor antibacterial response as bacterial contamination of tissues and extracellular fluids is very rapid. It has been proposed that MRLS also includes an immunosuppressive mechanism which predisposes the affect ed horses to opportunistic bacterial infection (Flaminio et al, 2005). Pathological lesions when MRLS is suspected are consistent with bacterial infection as the cause. Streptococcus, Actinobacillus species and Serratia were some of the prominent bacterial species isolated from horses suffering from MRLS. Sebastian M.M. et al (2008) propose two hypotheses for MRLS. According to one, the syndrome is produced due to an Eastern tent caterpillar toxin complicated with secondary bacterial

HOSPITALITY OPERATIONS MANAGEMENT Case Study Example | Topics and Well Written Essays - 2750 words

HOSPITALITY OPERATIONS MANAGEMENT - Case Study Example According to Phillip Kotler the key stages in product and service development are; idea generation, screening of processes, evaluation of concept, product or service development, and commercialization process. With respect to hospitality management the key stages in product and service development are market research, segmentation, idea generation and evaluation, product and service development, and advertising Heineke, & Davis (2007). It is an organized effort to collect relevant information about target customers Akkerman, Farahani, & Grunow, (2010). Market research provides useful information about customer likes, needs, and wants. It is an essential component of business strategy. For hospitality management it is necessary to identify what customers want before the development of any new product or service. It helps the company to develop products and services that meet customers’ expectations and to increase market share. Market segmentation means divide the market into small segments. It is a marketing strategy that segments the large market into small subsets of customers. It facilitates the company to select one or two specific segments and design the products or services according to the needs and wants of those particular segments. It is impossible to satisfy the needs of all customers so companies divide the market into small segments and then designs their products and services according to those segments which they want to serve. Idea generation is the result of market research and segmentation. This process develops the ideas based on customer needs and expectations. Initially companies generate many ideas and then screen them one by one on the basis of the feasibility and opportunity cost. In the idea generation process especially for hospitality management the ideas can be collected from existing loyal customers, employees, media, and also from strong competitors Yu, (2012). After ideas generation

Morality and God Essay Example for Free

Morality and God Essay Morality only exists if we believe in God; therefore if God doesn’t exist there is no morality. There have been so many evil acts committed in the name of God that it is difficult to maintain that a belief in God equates to morality. There are situations that happen every day where decisions are made based off of human rights that contradict the word of God. Morality comes from within, it is an understanding of right versus wrong and the ability to choose what is right. Knowing all this a belief in God is not a requirement for a person to be moral. (Mosser, 2011) We are taught that morals are basically the difference between right and wrong. A child may be taught that stealing is wrong because it hurts the store owner and can ruin the child’s reputation. Or the child may be told that if they steal they will be punished because God is always watching. The child has learned the fundamental difference between right and wrong, even if the reasoning is different. This will allow the child to make moral decisions when they grow up whether it is based off of human compassion or fear of God. If we accept that the child understands right from wrong regardless of their reason, we accept that God is not a requirement to be a moral person. If a person observes an act of violence or torture, they are morally required to stop it. In biblical times these acts were not only accepted but encouraged by the bible. Today, a person would not ignore these things simply because they did not believe in God. There are human rights that we believe each person is entitled to and someone with good morals would help out another person in need because it is the right thing to do. If it turned out that God does not exist, violence and torture would not suddenly become acceptable. (Mosser, 2011) Mass acceptance of a belief does not make it right. Ancient religions that believed in numerous gods have been pushed aside as fairy tales, for the more widely accepted belief in a single God. During their time those gods were prayed to just as fervently as today’s God. What was accepted as true back then is now known as a fable, and the laws of the day have been wiped away and replaced with our modern laws. These laws were put in to place to punish people who do wrong to others. They have become the moral balance. If you do wrong you will be punished, if you continue to do what is right you will live unmolested and enjoy your freedoms. God is not a requirement for someone to act morally, because there are earthly punishments for crimes. There is no right or wrong without God because He determines what is right and wrong. Moral standards cannot be enforced without God to ensure that we are punished or rewarded for our acts. Someone who does not believe in God may change their morals to whatever suits them at the time. We have been given guidelines by God on what is morally acceptable, and informed of the punishment that comes with being immoral. When an individual does not believe in God they cannot be a moral person, because they have no moral standards. (Millard, A. 2000) The Ten Commandments give us a basic understanding of what is right and wrong. These Commandments along with various scriptures from the bible determine which acts are moral and which are immoral. An individual who witnesses a crime but does not believe in God can simply decide that they are not responsible for stopping the crime. This may lead one to believe that if a non-believer does something right that they have morals. This is not the case, because they could just as easily do wrong and their conscience would have been just as clear. They have no moral compass to tell them that this act is leading them astray from God. (Riskin, S. 2007) If one does not believe in God they cannot know right from wrong and cannot do what is right because they do not have the understanding. The lack of a belief in God means that rules do not have to be followed. If you do not fear the wrath of God, there is nothing to stop you from committing immoral acts, or any crimes for that matter. Any situation can be overlooked because there is no fear of punishment without a fear of God. Only a person with a firm belief in God can be considered moral because they fear His punishment and desire his reward. God is the only person great enough to enforce moral standards, without his guidance there can be no binding morals. Moral standards come from God and without Him a person cannot be moral. When we talk in absolutes we ignore possibilities that exist outside of our beliefs. There are many examples of individuals that believed in God who acted immorally, as well as examples of people who do not believe in God acting with good morals. Their beliefs do not determine their morality, their acts do. If we are to base morality solely on a belief in God then which believer do we follow? Do we follow the believer who commits crimes, or only the believer who is an upstanding member of society? Adolf Hitler was raised as a Catholic, and in his adult life spoke of his religious beliefs. He wanted to create a pure Germany, through a religion known as positive Christianity. Positive Christianity removed the Jewish elements from the standard Christianity doctrine and replaced them with Nazi philosophy. More than six million Jewish people were killed during the Holocaust in the ideal of positive Christianity. Bill Gates is noted as saying he does not know if there is a God or not, yet he donates billions of dollars to Charity every year. The foundation he formed with his wife to address extreme poverty and poor health in third world countries has brought attention and relief to millions of people across the globe. These acts were not done in the hopes that they would be rewarded, but instead to help the human condition. A general concern about the welfare of our neighbors is not exclusive to God. Not every action is based solely off of a person’s morals. There are many reasons people decide to do things and we cannot judge a person’s moral standing off of a single action. We do not look at Adolf Hitler and say that he is a great moral figure because he believed in God. On the same note we do not look at Bill Gates, a non-believer and say that he is immoral. We look at their actions over time and determine whether or not they acted morally. We know that killing millions of innocent people is immoral; just as we know that helping sick and injured people is moral. Which God you believe in determines what you consider to be moral. Muslims agree that polygamy is acceptable. Protestants and the Jewish believe divorce is acceptable if certain conditions are met. Catholics are strictly against both polygamy and divorce. Which God is morally right? All of these groups worship the same God, so perhaps it is the translation of the word of God that is in question. When we look at this we begin to have a better understanding that God’s contradictory words could bring the thought of what is moral crumbling down. There are many controversial moral endorsements in the bible that are accepted today. There are also commands given that are ignored because they are no longer socially accepted as truth. Exodus 20:13 says we must not kill. However, Leviticus 20:13 tells us that if a man lies with another man he must be put to death. There are many debates and arguments over whether homosexuality is moral, but we overlook the second part of the scripture because it is no longer held as a valid punishment. The times have changed and we cannot murder or we will go to jail. Leviticus 19:19 says it is a sin to wear clothes made from two different types of material. You will be hard pressed to find anyone backing up this claim today. (King James Bible) Many religious people have chosen scripture from the bible to suit their lifestyles over the years, but ignore things that are no longer socially accepted as immoral. They hold others to strict standards on matters that they do not agree on and use verses from the bible to support their viewpoint. If everyone used the internal right versus wrong approach to morality there would be less confusion on which standards we held each other to. It is unfair to condemn someone for something using half of a statement from the bible, and then ignore the rest of the statement because it does not agree with current beliefs. Our faith, lessons from our parents or even witnessing other people’s actions are different reasons to decide what we believe is moral. All three have flaws that can lead to differing views on the same subject. However, at the end of the day there are certain things that everyone accepts as morally right, or morally wrong. These are situations where it does not matter how you learned it, you just know it. Biblical teachings tell us that certain things are acceptable, while others are punishable by death. But in the legal society of America acting on the acceptable things will land you in prison, and the immoral sins are inalienable rights. Every day decisions are made across the world without having to consider if we will be punished by a higher being. These things prove that a person does not have to believe in God to act morally. A moral person is someone who not only understands the difference between right and wrong, but also does what is right. The lack of God in someone’s life doesn’t make a person immoral just as the presence of God does not make someone moral. Morality is not proven by a belief in God. References King James Bible Millard, A. (2000). How reliable is exodus? Biblical Archaeology Review, 26(4), 50-57. Retrieved from http://search. proquest. com/docview/214908737? accountid=32521 Mosser, K. (2011). Logic an introduction. San Diego: Bridgepoint Education, Inc. Riskin, S. (2007). Ten commandments audience? Washington Jewish Week. Retrieved from http://search. proquest. com/docview/220857354? accountid=32521.

MicroRNA-21 Concentrations in Breast Cancer

MicroRNA-21 Concentrations in Breast Cancer Direct Serum Assay for MicroRNA-21 Concentrations in Early and Advanced Breast Cancer Abstract Background Small noncoding RNA molecules known as microRNAs (miRs) are involved in the regulation of gene expression. The hypothesis was based on the biomarker, miR-21 present in the serum, which related to the presence and stage of breast cancer. The direct application of reverse-transcription quantitative real-time PCR (RT-qPCR) in a direct serum assay has been used for the quantification and detection of the miR-21 in breast cancer patients. Methods A total of 102 breast cancer patients with varying stages of breast cancer and 20 healthy female patients were tested by the RT-qPCR applied directly in serum assay for miR-21. Results Detection for RT-qPCR-DS was limited to 0.625 µl of serum. miR-21 levels detected in the healthy donors were comparatively lower with respect to breast cancer patients with different stage of the disease. A significantly higher levels of miR-21 was detected in patients with stage IV breast cancer compared to patients with other stages of the disease. The odds ratio was 1.796 and area under the curve was 0.721 for the distinction of loco regional breast cancers and healthy donors. Multivariate analysis confirmed that a correlation of miR-21 concentrations and stage of breast cancer existed. Conclusion- The novel RT-qPCR-DS serves as a better technique in detecting circulating miR. miR-21 proves to be a significant biomarker for breast cancer, which could also probably detect the progression of the disease. Further research could lead to improved breast cancer care by this serum biomarker as a key tool. EVALUATION Traditional methods Mammography (also known as film mammography) is a traditional method for screening breast cancer (Boyd et al., 2007). Its principle lies in the use of low-dose x-rays. Soft tissue such as fat is radiographically lucent, which appears dark on a mammogram. In contrast, stroma and epithelial tissue are radiographically dense, which is termed mammographic density, appearing light on a mammogram (Boyd et al., 2007). It has been established that the more immense the density, the more association it had with regard to the greater risk of breast cancer. A dense tissue present in 75% or more of the breast poses a risk of breast cancer (Boyd et al., 2007).   A limitation of this method revolves around the fact that expansive mammographic density may be difficult to detect by mammography, thereby indicating a false negative (Boyd et al., 2007). Cancers may be masked by surrounding dense breast tissue, limiting the sensitivity of the screening (Boyd et al., 2007), thereby increasing the risk o f breast cancer (Pisano et al., 2005). High false positive results and costs are drawbacks of mammography (Asaga et al., 2010).   An alternative breast cancer screening technique is the MRI, which is sensitive, but its limitations include the lack of cost-effectiveness and specificity (Esserman et al., 2007). Digital mammography, an upgrade to film mammography allowed the manipulation of the degree of contrast on digital images. This allowed the differentiation of dense breast tissues from malignant cells (Pisano et al., 2005). Women under 50 years of age, with dense breast tissue or those who are pre-menopausal or peri-menopausal were mostly detected by digital mammography (Pisano et al., 2005). In comparison to the film mammography method, digital mammography has an increased cost (1.5-4 times more), but is quicker at developing the image (Pisano et al., 2005). BRCA1 and BRCA2 are tumour markers used to identify individuals who are at risk of developing breast cancer via inheritance (Duffy, 2001). Only 5-10% cases of breast cancers are hereditary. 80-85% risk of developing breast cancer was reported in individuals carrying either the BRCA1 or BRCA2 gene (Duffy, 2001). Cancer antigen 15-3 (CA 15-3) is a gene product of the MUC1 gene. Overexpression of MUC1 gene in malignant breast tumours allows CA 15-3 to be used as a tumour marker for breast cancer (Kabel, 2017). False positive results were reported in benign breast and benign liver diseases (Kabel, 2017). The serum concentration of patients with elevated levels of CA 15-3 became more detectable as the size of tumour and severity of the disease increased. Therefore, this is suitable as a prognostic and pharmacokinetic biomarker (Kabel, 2017). The lack of sensitivity for women with early disease have been a main limitation of CA 15-3 biomarker (Duffy et al., 2010). Rising levels of another extensively used biomarker, carcinoembryonic antigen (CEA) indicated poor treatment or the risk of recurrence following treatment (Kabel, 2017). The lack of disease sensitivity and specificity prevents the use of CEA as predictive biomarker (Kabel, 2017). Estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor-2 (HER-2) serve as pharmacokinetic biomarkers (Kabel, 2017). Relevance to current article Elevated levels of miR-21 was observed in breast cancer patients (N = 102) compared to healthy females (N = 20) in the study done by Asaga et al., (2010). Detection of circulating miR by RT-qPCR-DS was robust and effective (Asaga et al., 2010). The differentiation of patients with stage I, stage II or stage III from patients with stage IV breast cancer was possible with the direct assay, but not by the standard RT-qPCR (Asaga et al., 2010). The assay had a sensitivity and specificity of 67% and 75% respectively in distinguishing loco regional breast cancer patients from healthy patients. The specificity and sensitivity in distinguishing patients with stage IV breast cancer from the earlier stages was 86% and 70% respectively (Asaga et al., 2010). The use of the novel RT-qPCR in direct serum assay reduced mechanical and human errors and minimized the time and overall cost (Asaga et al., 2010). CA 15-3 and CEA are low in sensitivity and specificity, therefore cannot be used as a diagnostic marker (Ng et al., 2013). Comparatively, miR-21 shows a better specificity and sensitivity (Asaga et al., 2010). Current methods 3D mammography is an evolution of the mammography technology (Houssami et al., 2017). 3D mammography improves cancer visibility by reducing the images of overlapping breast tissue, leading to the visualization of benign and malignant breast lesions which would have been masked in traditional mammography (Houssami et al., 2016). It may also decrease the false positive recall. Cost and time-taken to read a 3D mammography are limitations of this method (Houssami et al., 2017). A study by Ng et al., (2013) detected elevation in miR-451, miR-16 and miR-21, while a reduction in miR-145 was observed in the plasma of breast cancer patients. The combination of miR-451 and miR-145 served as the best biomarkers for breast cancer with an optimal specificity of 92% and optimal sensitivity of 90% in distinguishing breast cancer patients from control subjects of other types of cancers (gastric cancer, lung cancer) recruited in the study (Ng et al., 2013). This study by Ng et al., (2013) recognized a combination of miRNAs specific to breast cancer and not the other cancers. Drawbacks include the lack of information regarding whether these miRNAs can be used to distinguish between the subtypes of breast cancer and between sporadic and familial forms (Ng et al., 2013). The study done by Asaga et al., (2010) only focused on miR-21 as a predictive marker in breast cancer, but miR-21 has been implicated in other types of cancer too. Comparatively the study done by Ng et al. , (2013) has identified biomarkers specific to breast cancer. In conclusion, the use of miR-21 as a biomarker in breast cancer presented a correlation of circulating miR-21 with the stage of breast cancer. More research is required to establish miR-21 as an important biomarker in breast cancer (Asaga et al., 2010). A combined expression analysis of miR-21 and miR-191 increased the specificity to 100% and sensitivity to 92% (Chen and Wang, 2013). The study done by Chen and Wang (2013) proved that a combination of miRNAs were better as a predictive biomarker for breast cancer. WORD COUNT ABSTRACT 243 EVALUATION 1039 REFERENCES Asaga, S., Kuo, C., Nguyen, T., Terpenning, M., Giuliano, A. and Hoon, D. (2010). Direct Serum Assay for MicroRNA-21 Concentrations in Early and Advanced Breast Cancer. Clinical Chemistry, 57(1), pp.84-91.Boyd, N., Guo, H., Martin, L., Sun, L., Stone, J., Fishell, E., Jong, R., Hislop, G., Chiarelli, A., Minkin, S. and Yaffe, M. (2007). Mammographic Density and the Risk and Detection of Breast Cancer. The New England Journal of Medicine, 356(3), pp.227-236. Chen, J. and Wang, X. (2013). MicroRNA-21 in breast cancer: diagnostic and prognostic potential. Clinical and Translational Oncology, 16(3), pp.225-233. Duffy, M. (2001). Biochemical markers in breast cancer: which ones are clinically useful?. Clinical Biochemistry, 34(5), pp.347-352. Duffy, M., Evoy, D. and McDermott, E. (2010). CA 15-3: Uses and limitation as a biomarker for breast cancer. Clinica Chimica Acta, 411(23-24), pp.1869-1874. Esserman, L., Shieh, Y., Park, J. and Ozanne, E. (2007). A role for biomarkers in the screening and diagnosis of breast cancer in younger women. Expert Review of Molecular Diagnostics, 7(5), pp.533-544. Houssami, N., Là ¥ng, K., Bernardi, D., Tagliafico, A., Zackrisson, S. and Skaane, P. (2016). Digital breast tomosynthesis (3D-mammography) screening: A pictorial review of screen-detected cancers and false recalls attributed to tomosynthesis in prospective screening trials. The Breast, 26, pp.119-134. Houssami, N., Bernardi, D., Pellegrini, M., Valentini, M., Fantà ², C., Ostillio, L., Tuttobene, P., Luparia, A. and Macaskill, P. (2017). Breast cancer detection using single-reading of breast tomosynthesis (3D-mammography) compared to double-reading of 2D-mammography: Evidence from a population-based trial. Cancer Epidemiology, 47, pp.94-99. Kabel, A. (2017). Tumor markers of breast cancer: New prospectives. Journal of Oncological Sciences. Ng, E., Li, R., Shin, V., Jin, H., Leung, C., Ma, E., Pang, R., Chua, D., Chu, K., Law, W., Law, S., Poon, R. and Kwong, A. (2013). Circulating microRNAs as Specific Biomarkers for Breast Cancer Detection. PLoS ONE, 8(1), p.e53141. Pisano, E., Gatsonis, C., Hendrick, E., Yaffe, M., Baum, J., Acharyya, S., Conant, E., Fajardo, L., Bassett, L., DOrsi, C., Jong, R. and Rebner, M. (2005). Diagnostic Performance of Digital versus Film Mammography for Breast-Cancer Screening. New England Journal of Medicine, 353(17), pp.1773-1783.

Healthsouth: The Rise and Fall Essay -- essays research papers

Running head: HEALTHSOUTH: THE RISE AND FALL HealthSouth: The Rise And Fall Abstract Richard Scrushy (Scrushy) had a vision and was driven by his leadership and entrepreneurial abilities. Scrushy was the mastermind and major creator of HealthSouth Corporation (HealthSouth). Scrushy served as chairman and Chief Executive Officer (CEO) of the corporation for more than 20 years. A Biographical Sketch: Richard Scrushy and HealthSouth. Retrieved March 22, 2005, from the World Wide Web: http://www.richardscrushy.com/biography.aspx. The U.S. Securities and Exchange Commission charged HealthSouth Corporation and CEO Richard Scrushy with fraud, alleging the earnings of HealthSouth have been extremely overstated since approximately 1999. Bassing, T. (2003, March 19). SEC charges Scrushy; 41.4B civil fraud alleged. Birmingham Business Journal. Retrieved March 23, 2005, from World Wide Web: http://birmingham.bizjournals.com/birmingham/stories/2003/03/17/daily30.html?t=printable. Scrushy has been replaced Jay Grinney (Grinney) who recently accepted the position of President and C EO of HealthSouth. Grinney has a vision for HealthSouth and is confident he will succeed in restoring the corporation to its original status of leadership in the world of healthcare. HealthSouth: The Rise and Fall   Ã‚  Ã‚  Ã‚  Ã‚  Richard Scrushy (Scrushy) was born in Selma, Alabama in 1952. He had two siblings which consisted of an older sister and a younger brother. Scrushy was raised by two working parents and the family attended a local Methodist Church located in Selma. As a young boy, Richard was always able to find a job making money. His entrepreneur endeavor’s emerged during his teenage years and continued there after. A Biographical Sketch: Richard Scrushy and HealthSouth. Retrieved March 22, 2005, from the World Wide Web: http://www.richardscrushy.com/biography.aspx.   Ã‚  Ã‚  Ã‚  Ã‚  Scrushy chose to continue his education beyond high school and was graduated from college, but not before marrying his first wife and becoming the father of two children. During his years in higher education, he became interested in respiratory therapy and enrolled in the respiratory therapy program at the University of Alabama at Birmingham (UAB). Scrushy was intellectually gifted, had excellent leadership abilities and quickly began climbing the corpo... ...ushy Please Step Forward, The New York Times A Biographical Sketch: Richard Scrushy and HealthSouth. Retrieved March 22, 2005, from the World Wide Web: http://www.richardscrushy.com/biography.aspx. Rehab Resource (March 1, 2005). Administrator’s Corner, Volume 5, Issue 3 Retrieved March 22, 2005 from the World Wide Web: Institute For Global Ethics, November 10, 2003, http://www/globalethics.org/newsline/members/issue.tmpl?articleid=11100316510695 Retrieved March 22, 2005 from the World Wide Web: U.S. Department of Justice, September 29, 2004, www.usdoj.gov/usao/aln Retrieved March 22, 2005 from the World Wide Web: http://www.al.com/specialreport/birminghamnews/healthsouth/scrushypay.jpg Retrieved April 5, 2005 from the World Wide Web: http://www.healthsouth.com/medinfo/home/app/frame. Retrieved April 5, 2005 from the World Wide Web: http://www.al.com/specialreport/birminghamnews/healthsouth/index.ssf   Ã‚  Ã‚  Ã‚  Ã‚   Retrieved April 5, 2005 from the World Wide Web: http://www.usatoday.com/money/industries/health/2004-10-25-scrushy-cover_x.htm Retrieved April 6, 2005 from the World Wide Web: A Guide To The Sarbanes-Oxley Act, 2002. http://www.soxlaw.com/

Culture and Identity Essay -- Cultural Identity Essays

Culture and Identity Culture and identity could have many different definitions. Culture to me is what made you the person that you are today. The background and history of a person that is the reason of who they are and what they stand for. Identity to me is the certain characteristics that belong to a person that makes them different from everyone else on this planet. The world with no culture or a lack of identity would be a rather boring place. Identity and culture are what makes this world an interesting place, there is a distinct relationship between identity and culture and one without the other they could not exists. In the essay "Real Indians Eat Jell-O" by Laurie Carlson, it seems that she has trouble finding her own identity and culture. Carlson a native american living in a trailer park in Montana wants to know more of her culture to try to give herself an identity. Carlson states "Indian kids are supposed to live in wide open spaces, in deserts or forests. They have horses and coyotes and wise grandparents" (Carlson par. 2). Instead of making her own identity and learning about her culture now, she wants have the identity of someone else, she wants the identity of Indians from hundreds and hundreds of years ago. She looks to her grandmother for culture and does not like what her grandmother has to say, Carlson wants to hear stories of beadwork and tales of coyotes while her grandmother while her grandmother taps her "primrose passion" colored nails to the song on the radio and tells her "Honey, be yourself"(Carlson par. 7). Personally that is the best answer anyone could give a child who is looking to make an identity for themselves, because an identity is who you are and who you are is everything. Also Carls... ...more successful than my parents just like they were more successful then my grandparents and like my grandparents were more successful then my great-grandparents. My community culture growing up has given me the hardworking, go getting attitude that I need in life to grow up to be a successful person in this world. Culture and identity have a very close knit relationship between them. A persons culture helps them to determine their identity in life. Without knowing your own culture, weather it be a poor indian growing up in a trailer park or a rich white boy growing up in a huge house, your identity would be very hard to determine. A persons culture is the main part of a persons identity, and without knowing your culture it would be hard to figure out ones identity. Works Cited Carlson, Laurie. "Real Indians Eat Jell-O". Northern Lights. (Spring 1993).

Generally Accepted Accounting Principles and Contribution Margin

Escareno Corporation has provided its contribution format income statement for June. The company produces and sells a single product. Sales (8,400 units): ($) 764,400 Variable expenses: ($) 445,200 Contribution margin: ($) 319,200 Fixed expenses: ($) 250,900 Net operating income: ($) 68,300 If the company sells 8,200 units, its total contribution margin should be closest to: Merchandise with a sales price of $500 is sold on account with term 2/10, n/30. The journal entry to record the sale would include a: Davison Company has fixed costs of $ 315,000 and a contribution margin ratio of 34%. If sales are expected to be $1,500,000, what is the margin of safety percent? † E. (114 points) The Beer toxin is composed of two subunits, Ping and Pong . The toxin binds to the Springbreak receptor on the plasma membrane of pancreatic cells and enters the cell via clathrin-mediated endocytosis. Once the toxin-receptor complex reaches the early endosome, Ping , Pong , and Springbreak dissociate from one another. Ping exits the early endosomes and enters the cytosol whereas Springbreak is targeted to the lysosomes for degradation. Although Ping alone can interact with Springbreak , its cytosolic targeting requires the presence of†¦ The vice-president of marketing and the director of human resources have developed a proposal whereby the company would compensate the sales sales force on a strictly commission basis using 20% of net sales. Given the increased incentive, they expect net sales to increase by 15%. As a result, they estimate that gross profit will increase by $53,061 and operating expenses by $88,322. Compute the expected new net income. (Hint: You do not need to prepare an income statement). A trial balance before adjustments included the following: Debit Credit Sales $425,000 Sales returns and allowance $14,000 Accounts receivable 43,000 Allowance for doubtful accounts 760 If the estimate of uncollectibles is made by taking ten percent of gross account receivables, the amount of the adjustment is $3,540. 4,224. $5,060. $4,300. Recently Asked Questions A substance, X, has the following properties. (Size of mass is 250. g. ) Specific Heat Capacities Hvap 20. kJ/mol C(s) 3. 0 J/g C Hfus 5. 0 kJ/mol C(l) 2. 5 J/g C bp 75 C C(g) 1. 0 J/g C mp -15 C Calculate the energy that must be removed to convert substance X from a gas at 113 C to a solid -54. 2 C. Assume X has a molar mass of 75. 0 g/mol. A doctor has applied for a patent on new technology, involving the use of advanced compu ters to create a new type of organism. One goal is to genetically alter these organisms for use in human organ growth and transplant. The doctor says that, if she is not granted a patent, she will continue her research. Write a 1,750- to 2,800-word paper, addressing the scenario. Address the following questions in your paper: o Should the doctor s activity be considered a violation of the law, a deviant act, or neither? o If this activity is a violation of the law